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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEUPROLIDE
| LEUPROLIDE | ANTINEOPLASTIC | INJECTION INTRAMUSCULAR IMPLANTATION SUBCUTANEOUS ORAL | Cmax 8.6 NANOMOLAR Tmax 4 HOUR VD 27 LITER PPB 46 PERCENT Cl 7.6 LITER / HOUR HT 3 HOUR | GONADOTROPIN-RELEASING HORMONE RECEPTOR | GONADOTROPIN-RELEASING HORMONE RECEPTOR AGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTOR | EMA | |||
