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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VALPROIC ACID
| VALPROIC ACID DIVALPROEX VALPROATE | NERVOUS SYSTEM | ORAL INJECTION | Cmax 563 MICROMOLAR Tmax 3.5 HOUR F 90 PERCENT VD 11 LITER PPB 82 PERCENT Cl 0.56 LITER / HOUR HT 12.5 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | SUCCINATE SEMIALDEHYDE DEHYDROGENASE INHIBITOR CHEMBL1911 SUCCINATE SEMIALDEHYDE DEHYDROGENASE P51649 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL HOMO SAPIENS ENZYME REDUCTASE | EMA | ||||
