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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METOPROLOL
| METOPROLOL |
CARDIOVASCULAR | ORAL INJECTION | Tmax 1 HOUR F 50 PERCENT VD 201.5 LITER (65 KILOGRAM) PPB 12 PERCENT Cl 50.7 LITER / HOUR (65 KILOGRAM) HT 5 HOUR SOLUBILITY VERY SOLUBLE IN WATER | BETA-1 ADRENERGIC RECEPTOR | BETA-1 ADRENERGIC RECEPTOR ANTAGONIST CHEMBL213 BETA-1 ADRENERGIC RECEPTOR P08588 BETA-1 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
