| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CIMETIDINE
| CIMETIDINE | METABOLISM | ORAL INJECTION | Tmax 1.1 HOUR VD 78 LITER (65 KILOGRAM) PPB 22 PERCENT Cl 31.6 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | HISTAMINE H2 RECEPTOR | HISTAMINE H2 RECEPTOR ANTAGONIST CHEMBL1941 HISTAMINE H2 RECEPTOR P25021 HISTAMINE H2 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTOR | EMA | |||
