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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NIACINAMIDE

NIACINAMIDENATURAL MOLECULE (link)


ATC A11HA01

METABOLISM
VITAMIN B3
ENZYME COFACTOR
ANTI-PELLAGRA
ANTIPRURITIC
ANTIMICROBIAL
PHOTO-PROTECTIVE
SEBOSTATIC

INJECTION ORAL INTRAVENOUS

PDB 2E5D (CRYSTAL STRUCTURE OF HUMAN NMPRTASE COMPLEXED WITH NICOTINAMIDE)

LIGAND CODE = NCA (link to the list of PDB complexes)

Download experimental 3D coordinates of NCA with added hydrogens

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