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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LACTULOSE
| LACTULOSE | METABOLISM | ORAL RECTAL | SOLUBILITY FREELY SOLUBLE IN WATER | EVOLVED BETA-GALACTOSIDASE SUBUNIT ALPHA PDB 3W9T (PORE-FORMING CEL-III) LIGAND CODE = W9T (link to the list of PDB complexes) Download experimental 3D coordinates of W9T with added hydrogens | Unknown - more at DrugCentral | EMA | |||
