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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PROPRANOLOL
| PROPRANOLOL |
CARDIOVASCULAR | ORAL INJECTION | Tmax 2.5 HOUR VD 260 LITER (65 KILOGRAM) PPB 90 PERCENT Cl 46.8 LITER / HOUR (65 KILOGRAM) HT 4.5 HOUR SOLUBILITY READILY SOLUBLE IN WATER | BETA ADRENERGIC RECEPTOR PDB 5FUK (CRYSTALLIZATION OF A DIMERIC HEME PEROXYGENASE FROM THE FUNGUS MARASMIUS ROTULA) LIGAND CODE = SNP (link to the list of PDB complexes) Download experimental 3D coordinates of SNP with added hydrogens | BETA-2 ADRENERGIC RECEPTOR ANTAGONIST CHEMBL210 BETA-2 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
