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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METRONIDAZOLE
| METRONIDAZOLE |
ANTIINFECTIVES | ORAL INJECTION TOPICAL VAGINAL | Cmax 233.9 MICROMOLAR Tmax 1.5 HOUR VD 26 LITER (65 KILOGRAM) PPB 20 PERCENT Cl 3.3 LITER / HOUR (65 KILOGRAM) HT 8 HOUR SOLUBILITY IN WATER OF 10 MILLIGRAM / MILLILITER AT 20 DEGREE CELCIUS | PDB 1W3R (NIMA FROM D. RADIODURANS WITH METRONIDAZOLE AND PYRUVATE) LIGAND CODE = 2MN (link to the list of PDB complexes) Download experimental 3D coordinates of 2MN with added hydrogens | DNA INHIBITOR CHEMBL2364041 DNA BACTERIA | EMA | |||
