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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TALETRECTINIB
| TALETRECTINIB | ANTINEOPLASTIC | ORAL | Cmax 1.2 MICROMOLAR Tmax 4 HOUR VD 9820 LITER PPB 96 PERCENT Cl 63 LITER / HOUR HT 66 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | TYROSINE KINASE ROS1 TRKA TRKB TRKC | - more at DrugCentral | EMA | |||
