| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SELADELPAR
| SELADELPAR | METABOLISM | ORAL | Cmax 231.7 NANOMOLAR Tmax 1.5 HOUR VD 133.2 LITER PPB 99 PERCENT Cl 12 LITER / HOUR HT 6 HOUR SOLUBILITY VERY SOLUBLE AT HIGH PH | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)-DELTA PDB 8HUO (X-RAY STRUCTURE OF HUMAN PPAR DELTA LIGAND BINDING DOMAIN-SELADELPAR CO-CRYSTALS OBTAINED BY CO-CRYSTALLIZATION) LIGAND CODE = KKB (link to the list of PDB complexes) Download experimental 3D coordinates of KKB with added hydrogens | - more at DrugCentral | EMA | |||
