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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DIFELIKEFALIN

DIFELIKEFALIN


ATC V03AX04

VARIOUS
TREATMENT OF PRURITUS ASSOCIATED WITH KIDNEY DISEASE (CKD-AP)
KAPPA OPIOID RECEPTOR AGONIST
SYNTHETIC PEPTIDE

INTRAVENOUS

VD 15.5 LITER (65 KILOGRAM)

PPB 25 PERCENT

HT 27 HOUR

SOLUBILITY SOLUBLE IN WATER

KAPPA OPIOID RECEPTOR

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