| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M SELUMETINIB (is an active metabolite)
| SELUMETINIB | ANTINEOPLASTIC | - | MEK1 MEK2 | Dual specificity mitogen-activated protein kinase kinase 1 INHIBITOR Q02750 (MP2K1_HUMAN) | EMA | ||||
