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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TAZEMETOSTAT
| TAZEMETOSTAT | ANTINEOPLASTIC | ORAL | Cmax 1.45 MICROMOLAR Tmax 1.5 HOUR F 33 PERCENT VD 1230 LITER PPB 88 PERCENT Cl 274 LITER / HOUR HT 3.1 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | METHYLTRANSFERASE EZH2 | Histone-lysine N-methyltransferase EZH2 inhibitor Q15910 EZH2_HUMAN | EMA | |||
