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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SOLRIAMFETOL

SOLRIAMFETOL


ATC N06BA14

NERVOUS SYSTEM
A DOPAMINE AND NOREPINEPHRINE REUPTAKE INHIBITOR (DNRI)
TREATMENT OF EXCESSIVE DAYTIME SLEEPINESS ASSOCIATED WITH NARCOLEPSY OR OBSTRUCTIVE SLEEP APNEA (OSA)

ORAL

Tmax 2 HOUR

F 95 PERCENT

VD 199 LITER

PPB 16.3 PERCENT

Cl 19.5 LITER / HOUR

HT 7.1 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

DOPAMINE TRANSPORTER
NOREPINEPHRINE TRANSPORTER

Sodium-dependent dopamine transporter Q01959EMA

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