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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ELAGOLIX

ELAGOLIX


ATC H01CC03

HORMONES
GONADOTROPIN-RELEASING HORMONE (GNRH) RECEPTOR ANTAGONIST
TREATMENT OF PAIN ASSOCIATED WITH ENDOMETRIOSIS

ORAL

Cmax 1.22 MICROMOLAR

Tmax 1 HOUR

VD 881 LITER

PPB 80 PERCENT

Cl 144 LITER / HOUR

HT 5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

GONADOTROPIN-RELEASING HORMONE RECEPTOR

Gonadotropin-releasing hormone receptor P30968EMA

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