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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PLAZOMICIN
| PLAZOMICIN | ANTIINFECTIVES | INTRAVENOUS | Cmax 124 MICROMOLAR VD 17.9 LITER PPB 20 PERCENT Cl 4.5 LITER / HOUR HT 3.5 HOUR | 30S RIBOSOMAL SUBUNIT PDB 6CD7 (CRYSTAL STRUCTURE OF APH(2)-IVA) LIGAND CODE = EDS (link to the list of PDB complexes) Download experimental 3D coordinates of EDS with added hydrogens | 30S ribosomal protein | EMA | |||
