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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LETERMOVIR
| LETERMOVIR | ANTIINFECTIVES | ORAL INTRAVENOUS | Cmax 22.7 MICROMOLAR Tmax 1.25 HOUR F 94 PERCENT VD 45.5 LITER PPB 99 PERCENT HT 12 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | DNA TERMINASE COMPLEX | ENZYME TRM1_HCMVM INHIBITOR F5HC79 TRM2_HCMVM INHIBITOR F5HGI9 TRM3_HCMVM INHIBITOR F5HCU8 | EMA | |||
