Cheminformatic Tools and Databases for Pharmacology

session 79388 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
VABORBACTAM

VABORBACTAM


ATC J01DH52

ANTIINFECTIVES
A BETA-LACTAMASE INHIBITOR
TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS (CUTI) INCLUDING PYELONEPHRITIS

INTRAVENOUS

Cmax 170.7 MICROMOLAR (4 GRAM)

VD 18.6 LITER

PPB 33 PERCENT

Cl 10.9 LITER / HOUR

HT 1.68 HOUR

BETA-LACTAMASE

PDB 4XUZ (STRUCTURE OF CTX-M-15 BOUND TO RPX-7009 AT 1.5 A)

LIGAND CODE = 4D6 (link to the list of PDB complexes)

Download experimental 3D coordinates of 4D6 with added hydrogens

Unknown - more at DrugCentralEMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |