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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PLECANATIDE

PLECANATIDE


ATC A06AX07

METABOLISM
TREATMENT OF CHRONIC IDIOPATHIC CONSTIPATION (CIC)
GUANYLATE CYCLASE-C AGONIST
STRUCTURALLY RELATED TO HUMAN UROGUANYLIN

ORAL

SOLUBILITY SOLUBLE IN WATER

GUANYLATE CYCLASE-C

ENZYME GUC2C_HUMAN AGONIST P25092EMA

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