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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PROMAZINE DISCONTINUED
| PROMAZINE | NERVOUS SYSTEM | ORAL INJECTION | VD 526.5 LITER (65 KILOGRAM) PPB 89 PERCENT Cl 54.6 LITER / HOUR (65 KILOGRAM) HT 7.9 HOUR | DOPAMINE RECEPTOR PDB 4MA7 (CRYSTAL STRUCTURE OF MOUSE PRION PROTEIN COMPLEXED WITH PROMAZINE) LIGAND CODE = P2Z (link to the list of PDB complexes) Download experimental 3D coordinates of P2Z with added hydrogens | D2-LIKE DOPAMINE RECEPTOR ANTAGONIST CHEMBL2331075 D2-LIKE DOPAMINE RECEPTOR P14416 D(2) DOPAMINE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR DOPAMINE RECEPTOR | EMA | |||
