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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ELBASVIR
| ELBASVIR |
ANTIINFECTIVES | ORAL | Cmax 137 NANOMOLAR Tmax 3 HOUR VD 680 LITER PPB 99.9 PERCENT HT 24 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | NS5A | GENOME POLYPROTEIN POLG_HCVH INHIBITOR P27958 POLG_HCVBK INHIBITOR P26663 POLG_HCVED INHIBITOR O39929 | EMA | |||
