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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DASABUVIR
| DASABUVIR |
ANTIINFECTIVES | ORAL | Cmax 1.35 MICROMOLAR Tmax 4.5 HOUR F 70 PERCENT VD 396 LITER PPB 99.5 PERCENT Cl 47.7 LITER / HOUR (EQN) HT 5.75 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | HCV NON-NUCLEOSIDE NS5B PALM POLYMERASE | HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE INHIBITOR CHEMBL5375 HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE Q8JXU8 NS5B PROTEIN HEPATITIS C VIRUS ENZYME TRANSFERASE | EMA | |||
