| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NALOXEGOL
| NALOXEGOL | METABOLISM | ORAL | Tmax 2 HOUR VD 1554 LITER PPB 4.2 PERCENT Cl 126 LITER / HOUR (EQN) HT 8.5 HOUR SOLUBILITY HIGH AQUEOUS SOLUBILITY ACROSS THE PHYSIOLOGIC PH RANGE | MU-OPIOID RECEPTOR | MU OPIOID RECEPTOR ANTAGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTOR | EMA | |||
