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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PREDNISONE
| PREDNISONE | METABOLISM | ORAL | Cmax 801 NANOMOLAR (PMID21982386) Tmax 2.2 HOUR VD 37 LITER (65 KILOGRAM) PPB 73 PERCENT Cl 11 LITER / HOUR HT 2.6 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR | GLUCOCORTICOID RECEPTOR AGONIST CHEMBL2034 GLUCOCORTICOID RECEPTOR P04150 GLUCOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C1 | EMA | |||
