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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIOCIGUAT
| RIOCIGUAT | CARDIOVASCULAR | ORAL | F 94 PERCENT VD 30 LITER PPB 95 PERCENT Cl 2.6 LITER / HOUR HT 9.5 HOUR SOLUBILITY IN WATER (4 MILLIGRAM / LITER) | SOLUBLE GUANYLATE CYCLASE | SOLUBLE GUANYLATE CYCLASE POSITIVE ALLOSTERIC MODULATOR CHEMBL2111348 SOLUBLE GUANYLATE CYCLASE O75343 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HOMO SAPIENS ENZYME LYASE GUANYLATE CYCLASE SOLUBLE GUANYLATE CYCLASE | EMA | |||
