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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PYRAZINOIC ACID (is an active metabolite)
| PYRAZINOIC ACID | ANTIINFECTIVES | - | MYCOBACTERIAL PYRAZINAMIDASE (PNCA) XANTHINE OXYDASE PDB 4NNI (STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE) LIGAND CODE = VGL (link to the list of PDB complexes) Download experimental 3D coordinates of VGL with added hydrogens | ENZYME P95029_MYCTU INHIBITOR P95029 | EMA | ||||
