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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CANAGLIFLOZIN
| CANAGLIFLOZIN |
METABOLISM | ORAL | F 65 PERCENT VD 119 LITER PPB 99 PERCENT Cl 11.5 LITER / HOUR HT 13.1 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER FROM PH 1.1 TO 12.9 | SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2) | SODIUM/GLUCOSE COTRANSPORTER 2 INHIBITOR CHEMBL3884 SODIUM/GLUCOSE COTRANSPORTER 2 P31639 SODIUM/GLUCOSE COTRANSPORTER 2 HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC05 | EMA | |||
