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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
INGENOL MEBUTATE

INGENOL MEBUTATE


ATC D06BX02

DERMATOLOGICALS
ACTINIC KERATOSIS
INDUCES CELL DEATH IS MEDIATED THROUGH THE PKC DELTA/MEK/ERK PATHWAY (PMID26116359)

TOPICAL

KINASE KPCD_HUMAN ACTIVATOR Q05655EMA

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