| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIVAROXABAN
| RIVAROXABAN | BLOOD | ORAL | F 90 PERCENT (10 MILLIGRAM) VD 50 LITER PPB 93 PERCENT Cl 10 LITER / HOUR HT 7 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | XA FACTOR PDB 2W26 (FACTOR XA IN COMPLEX WITH BAY59-7939) LIGAND CODE = RIV (link to the list of PDB complexes) Download experimental 3D coordinates of RIV with added hydrogens | COAGULATION FACTOR X INHIBITOR CHEMBL244 COAGULATION FACTOR X P00742 COAGULATION FACTOR X HOMO SAPIENS ENZYME PROTEASE SERINE PAS S1A | EMA | |||
