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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DEGARELIX
| DEGARELIX | ANTINEOPLASTIC | SUBCUTANEOUS | Cmax 16 NANOMOLAR (240 MILLIGRAM) VD 1000 LITER PPB 90 PERCENT Cl 9 LITER / HOUR HT 1272 HOUR | GONADOTROPIN-RELEASING HORMONE | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTOR | EMA | |||
