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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CALCIFEDIOL
| CALCIFEDIOL | NATURAL MOLECULE (link) METABOLISM | ORAL | 25(OH)D-1ALPHA-HYDROXYLASE PDB 1J78 (CRYSTALLOGRAPHIC ANALYSIS OF THE HUMAN VITAMIN D BINDING PROTEIN) LIGAND CODE = VDY (link to the list of PDB complexes) Download experimental 3D coordinates of VDY with added hydrogens | VITAMIN D RECEPTOR AGONIST CHEMBL1977 VITAMIN D RECEPTOR P11473 VITAMIN D3 RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR1 NR1I NR1I1 | EMA | ||||
