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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHOXSALEN
| METHOXSALEN | NATURAL MOLECULE (link) ANTINEOPLASTIC AGENTS | ORAL TOPICAL INJECTION | Cmax 1.15 MICROMOLAR (PMID3512141) Tmax 1.8 HOUR VD 325 LITER (65 KILOGRAM) Cl 345 LITER / HOUR (PMID3512141) HT 2 HOUR | DNA PDB 1Z11 (CRYSTAL STRUCTURE OF HUMAN MICROSOMAL P450 2A6 WITH METHOXSALEN BOUND) LIGAND CODE = 8MO (link to the list of PDB complexes) Download experimental 3D coordinates of 8MO with added hydrogens | DNA INHIBITOR CHEMBL2311221 DNA HOMO SAPIENS | EMA | |||
