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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SULBACTAM
| SULBACTAM | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 871 MICROMOLAR (446 MICROGRAM / KILOGRAM) VD 20.8 LITER (65 KILOGRAM) PPB 38 PERCENT Cl 19.8 LITER / HOUR (65 KILOGRAM) HT 1 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | BETA-LACTAMASE PDB 4FH2 (STRUCTURE OF S70C BETA-LACTAMASE BOUND TO SULBACTAM) LIGAND CODE = 0RN (link to the list of PDB complexes) Download experimental 3D coordinates of 0RN with added hydrogens | BACTERIAL BETA-LACTAMASE TEM INHIBITOR CHEMBL2364670 BACTERIAL BETA-LACTAMASE TEM P62593 BETA-LACTAMASE TEM BACTERIA ENZYME HYDROLASE | EMA | |||
