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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SERTACONAZOLE
| SERTACONAZOLE | IMIDAZOLE | TOPICAL | Cmax BELOW THE LIMIT OF QUANTITATION (2.5 NANOGRAM / MILLILITER) SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | CYTOCHROME P450 PDB 1TQN (HUMAN MICROSOMAL P450 3A4) | CYTOCHROME P450 51 INHIBITOR CHEMBL1780 CYTOCHROME P450 51 P10613 LANOSTEROL 14-ALPHA DEMETHYLASE CANDIDA ALBICANS (STRAIN SC5314 / ATCC MYA-2876) (YEAST) ENZYME CYTOCHROME P450 CYP_51 CYP_51A CYP_51A1 | EMA | |||
