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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SUMATRIPTAN
| SUMATRIPTAN | NERVOUS SYSTEM | SUBCUTANEOUS ORAL NASAL IONTOPHORESIS | Cmax 0.250 MICROMOLAR F 97 PERCENT VD 50 LITER PPB 21 PERCENT Cl 71.6 LITER / HOUR HT 1.9 HOUR | 5-HYDROXYTRYPTAMINE 1D RECEPTOR 5-HYDROXYTRYPTAMINE 1B RECEPTOR | SEROTONIN 1D (5-HT1D) RECEPTOR AGONIST CHEMBL1983 SEROTONIN 1D (5-HT1D) RECEPTOR P28221 5-HYDROXYTRYPTAMINE RECEPTOR 1D HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTOR | EMA | |||
