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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MILRINONE
| MILRINONE | CARDIOVASCULAR | INJECTION | VD 24.7 LITER (65 KILOGRAM) PPB 70 PERCENT Cl 8.4 LITER / HOUR (65 KILOGRAM) HT 2.3 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | CAMP 3',5'-CYCLIC PHOSPHODIESTERASE 3 PDB 1TLM (STRUCTURAL ASPECTS OF INOTROPIC BIPYRIDINE BINDING: CRYSTAL STRUCTURE DETERMINATION TO 1.9 ANGSTROMS OF THE HUMAN SERUM TRANSTHYRETIN-MILRINONE COMPLEX) LIGAND CODE = MIL (link to the list of PDB complexes) Download experimental 3D coordinates of MIL with added hydrogens | PHOSPHODIESTERASE 3A INHIBITOR CHEMBL241 PHOSPHODIESTERASE 3A Q14432 CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A HOMO SAPIENS ENZYME PHOSPHODIESTERASE PDE_3 PDE_3A | EMA | |||
