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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLECAINIDE
| FLECAINIDE | CARDIOVASCULAR | ORAL | VD 366 LITER PPB 48 PERCENT Cl 17.6 LITER / HOUR HT 12 HOUR SOLUBILITY 48.4 MILLIGRAM / MILLILITER | SODIUM CHANNEL NAV1.5 PDB 6MVX (NAVAB VOLTAGE-GATED SODIUM CHANNEL, I217C, IN COMPLEX WITH CLASS 1C ANTI-ARRHYTHMIC FLECAINIDE) LIGAND CODE = K4D (link to the list of PDB complexes) Download experimental 3D coordinates of K4D with added hydrogens | SODIUM CHANNEL PROTEIN TYPE V ALPHA SUBUNIT BLOCKER CHEMBL1980 SODIUM CHANNEL PROTEIN TYPE V ALPHA SUBUNIT Q14524 SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA HOMO SAPIENS ION CHANNEL VGC VG NA | EMA | |||
