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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| KETOPROFEN
| KETOPROFEN |
MUSCULO-SKELETEL SYSTEM | ORAL | Cmax 12.2 MICROMOLAR Tmax 1.25 HOUR F 90 PERCENT VD 6.5 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 6.9 LITER / HOUR HT 3.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | PROSTAGLANDIN G/H SYNTHASE 1 PROSTAGLANDIN G/H SYNTHASE 2 | CYCLOOXYGENASE INHIBITOR CHEMBL2094253 CYCLOOXYGENASE P23219 PROSTAGLANDIN G/H SYNTHASE 1 HOMO SAPIENS ENZYME REDUCTASE | EMA | |||
