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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CARPROFEN DISCONTINUED
| CARPROFEN | ANTIINFLAMMATORY | ORAL | PROSTAGLANDIN G/H SYNTHASE 2 PDB 4MJR (E. COLI SLIDING CLAMP IN COMPLEX WITH (S)-CARPROFEN) LIGAND CODE = 0LA (link to the list of PDB complexes) Download experimental 3D coordinates of 0LA with added hydrogens | CYCLOOXYGENASE-2 INHIBITOR CHEMBL230 CYCLOOXYGENASE-2 P35354 PROSTAGLANDIN G/H SYNTHASE 2 HOMO SAPIENS ENZYME REDUCTASE | EMA | ||||
