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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DYPHYLLINE DISCONTINUED

DYPHYLLINENATURAL MOLECULE (link)


ATC R03DA01
ATC R03DB01
ATC R03DA51

RESPIRATORY
BRONCHODILATOR AGENTS
PHOSPHODIESTERASE INHIBITORS
SMOOTH MUSCLE RELAXANTS
VASODILATOR AGENTS

ORAL INJECTION

Cmax 67 MICROMOLAR

VD 27.3 LITER (65 KILOGRAM)

Cl 18.7 LITER / HOUR (65 KILOGRAM)

HT 2 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

PHOSPHODIESTERASE

PHOSPHODIESTERASE 4 INHIBITOR CHEMBL2093863 PHOSPHODIESTERASE 4 P27815 CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A HOMO SAPIENS ENZYME PHOSPHODIESTERASE PDE_4 PDE_4AEMA

ANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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