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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EPIRUBICIN
| EPIRUBICIN | ANTINEOPLASTIC | INJECTION INTRAVENOUS | Cmax 17 MICROMOLAR VD 1365 LITER PPB 77 PERCENT Cl 69 LITER / HOUR HT 31 HOUR | DNA DNA HELICASE PDB 2DR6 (CRYSTAL STRUCTURE OF A MULTIDRUG TRANSPORTER REVEAL A FUNCTIONALLY ROTATING MECHANISM) LIGAND CODE = DM2_2DR6 (link to the list of PDB complexes) Download experimental 3D coordinates of DM2_2DR6 with added hydrogens | DNA TOPOISOMERASE 2-ALPHA P11388 DNA TOPOISOMERASE 2-ALPHA HOMO SAPIENS ENZYME ISOMERASE | EMA | |||
