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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| QUINUPRISTIN
| QUINUPRISTIN | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 3.1 MICROMOLAR VD 29 LITER (65 KILOGRAM) PPB 66 PERCENT Cl 46.8 LITER / HOUR (65 KILOGRAM) HT 0.85 HOUR | RIBOSOME STAPHYLOCOCCUS AUREUS VIRGINIAMYCIN B LYASE PDB 2Z2P (CATALYTICALLY INACTIVE H270A VIRGINIAMYCIN B LYASE FROM STAPHYLOCOCCUS AUREUS) | BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 23S RIBOSOMAL RNA BACTERIA | EMA | |||
