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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFEPIME
| CEFEPIME | ANTIINFECTIVES | INJECTION INTRAVENOUS | Cmax 340.7 MICROMOLAR F 82 PERCENT (IM) VD 18 LITER PPB 20 PERCENT Cl 7.2 LITER / HOUR HT 2 HOUR SOLUBILITY HIGHLY SOLUBLE IN WATER | PENICILLIN-BINDING PROTEIN PDB 5OJ0 (PENICILLIN-BINDING PROTEIN 2X (PBP2X) FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH CEFEPIME) LIGAND CODE = 9WT (link to the list of PDB complexes) Download experimental 3D coordinates of 9WT with added hydrogens | BACTERIAL PENICILLIN-BINDING PROTEIN INHIBITOR CHEMBL2354204 BACTERIAL PENICILLIN-BINDING PROTEIN P02918 PENICILLIN-BINDING PROTEIN 1A BACTERIA ENZYME PROTEASE SERINE UNCLASSIFIED | EMA | |||
