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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFTRIAXONE
| CEFTRIAXONE |
ANTIINFECTIVES | INTRAMUSCULAR INTRAVENOUS INJECTION | VD 9.6 LITER PPB 85 PERCENT Cl 1 LITER / HOUR (65 KILOGRAM) HT 7.25 LITER / HOUR SOLUBILITY IS READILY SOLUBLE IN WATER | GAMMA-GLUTAMYLTRANSPEPTIDASE PDB 5NZX (CRYSTAL STRUCTURE OF DNA CROSS-LINK REPAIR PROTEIN 1A IN COMPLEX WITH CEFTRIAXONE (ALTERNATIVE SITE)) LIGAND CODE = 9F2 (link to the list of PDB complexes) Download experimental 3D coordinates of 9F2 with added hydrogens | BACTERIAL PENICILLIN-BINDING PROTEIN INHIBITOR CHEMBL2354204 BACTERIAL PENICILLIN-BINDING PROTEIN P02918 PENICILLIN-BINDING PROTEIN 1A BACTERIA ENZYME PROTEASE SERINE UNCLASSIFIED | EMA | |||
