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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EDROPHONIUM DISCONTINUED
| EDROPHONIUM | METABOLISM | INJECTION | VD 71.5 LITER (65 KILOGRAM) Cl 37.4 LITER / HOUR (65 KILOGRAM) HT 1.8 HOUR | ACETYLCHOLINESTERASE PDB 2ACK (ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA) LIGAND CODE = EDR (link to the list of PDB complexes) Download experimental 3D coordinates of EDR with added hydrogens | ACETYLCHOLINESTERASE INHIBITOR CHEMBL220 ACETYLCHOLINESTERASE P22303 ACETYLCHOLINESTERASE HOMO SAPIENS ENZYME HYDROLASE | EMA | |||
