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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CHLORTETRACYCLINE DISCONTINUED
| CHLORTETRACYCLINE |
ANTIINFECTIVES | OPHTHALMIC | VD 58.5 LITER (65 KILOGRAM) PPB 48 PERCENT Cl 7.8 LITER / HOUR (65 KILOGRAM) HT 7 HOUR | 30S RIBOSOMAL PROTEIN PDB 2TCT (THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE) LIGAND CODE = CTC (link to the list of PDB complexes) Download experimental 3D coordinates of CTC with added hydrogens | BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 16S RIBOSOMAL RNA BACTERIA | EMA | |||
