| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DAPSONE
| DAPSONE | ANTIINFECTIVES | TOPICAL ORAL | VD 54 LITER (65 KILOGRAM) PPB 75 PERCENT Cl 1.8 LITER / HOUR (65 KILOGRAM) HT 22 HOUR | DIHYDROFOLATE REDUCTASE DIHYDROPTEROATE SYNTHASE | DIHYDROPTEROATE SYNTHASE 1 INHIBITOR CHEMBL2362993 DIHYDROPTEROATE SYNTHASE 1 P0C0X1 DIHYDROPTEROATE SYNTHASE 1 MYCOBACTERIUM LEPRAE (STRAIN TN) ENZYME TRANSFERASE | EMA | |||
