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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CONIVAPTAN
| CONIVAPTAN | CARDIOVASCULAR | INTRAVENOUS INJECTION | Cmax 1.24 MICROMOLAR VD 49.4 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 15.2 LITER / HOUR HT 5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | VASOPRESSIN V1A RECEPTOR VASOPRESSIN V2 RECEPTOR | VASOPRESSIN V2 RECEPTOR ANTAGONIST CHEMBL1790 VASOPRESSIN V2 RECEPTOR P30518 VASOPRESSIN V2 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE VASOPRESSIN AND OXYTOCIN RECEPTOR | EMA | |||
