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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CICLESONIDE (has an active metabolite)
| CICLESONIDE | RESPIRATORY | INHALATION NASAL | F 22 PERCENT VD 188 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 152 LITER / HOUR HT 0.71 HOUR | CORTICOSTEROID-BINDING GLOBULIN | GLUCOCORTICOID RECEPTOR AGONIST CHEMBL2034 GLUCOCORTICOID RECEPTOR P04150 GLUCOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C1 | EMA | |||
