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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| THEOPHYLLINE
| THEOPHYLLINE AMINOPHYLLINE | NATURAL MOLECULE (link)
RESPIRATORY SYSTEM | ORAL RECTAL INJECTION | VD 29.2 LITER (65 KILOGRAM) PPB 40 PERCENT Cl 2.5 LITER / HOUR (65 KILOGRAM) HT 8.7 HOUR | PHOSPHODIESTERASE III PHOSPHODIESTERASE IV PDB 1EHT (THEOPHYLLINE-BINDING RNA IN COMPLEX WITH THEOPHYLLINE, NMR, 10 STRUCTURES) LIGAND CODE = TEP (link to the list of PDB complexes) Download experimental 3D coordinates of TEP with added hydrogens | ADENOSINE RECEPTOR ANTAGONIST CHEMBL2111329 ADENOSINE RECEPTOR P0DMS8 ADENOSINE RECEPTOR A3 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL NUCLEOTIDE-LIKE RECEPTOR ADENOSINE RECEPTOR | EMA | |||
